WNK1 is required for mitosis and abscission.

  title={WNK1 is required for mitosis and abscission.},
  author={Szu-wei Tu and Abhijit C Bugde and Katherine Luby-Phelps and Melanie H Cobb},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={108 4},
WNK [with no lysine (K)] protein kinases are found in all sequenced multicellular and many unicellular organisms. WNKs influence ion balance. Two WNK family members are associated with a single gene form of hypertension. RNA interference screens have implicated WNKs in survival and growth, and WNK1 is essential for viability of mice. We found that the… CONTINUE READING