WINSTODEC: a stochastic deconvolution interactive program for physiological and pharmacokinetic systems

@article{Sparacino2002WINSTODECAS,
  title={WINSTODEC: a stochastic deconvolution interactive program for physiological and pharmacokinetic systems},
  author={Giovanni Sparacino and Gianluigi Pillonetto and Massimo Capello and Giuseppe De Nicolao and Claudio Cobelli},
  journal={Computer methods and programs in biomedicine},
  year={2002},
  volume={67 1},
  pages={67-77}
}
Deconvolution allows the reconstruction of non-accessible inputs (e.g. hormone secretion rate) from their causally-related measurable effects (e.g. hormone plasma concentration). Deconvolution is challenging under several aspects both general (e.g. determination of a suitable trade-off between data fit and solution smoothness in order to contrast ill-conditioning, assessment of the confidence intervals) as well as specific of physiological systems (e.g. non-uniform and infrequent data sampling… CONTINUE READING

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