WAFL, a new protein involved in regulation of early endocytic transport at the intersection of actin and microtubule dynamics.


We have previously identified a new gene with sequence homology to the WASP-family of actin regulators denoted WAFL (WASP and FKBP-like). Here we report a possible biological function for WAFL, by demonstrating an association to early endosomes via its central coiled-coil domain. Further we show by functional and structural studies that WAFL is associated… (More)
DOI: 10.1016/j.yexcr.2008.12.004