Vulvar keratinizing squamous cell carcinoma in a 26-year-old woman.
@article{Echeverri2001VulvarKS, title={Vulvar keratinizing squamous cell carcinoma in a 26-year-old woman.}, author={Carolina Echeverri and Mark H. Stoler and Philip T. Valente}, journal={Archives of pathology \& laboratory medicine}, year={2001}, volume={125 2}, pages={ 267-70 } }
A 26-year-old Hispanic woman complaining of "itching" and "herpetic lesions" on the vulva for 9 months was seen at a university hospital. On physical examination, multiple vulvar masses were noted. Biopsies taken from these lesions showed invasive keratinizing squamous cell carcinoma. The vulvectomy specimen revealed 4 tumor masses, the largest located on the mons pubis. Although the incidence of vulvar intraepithelial neoplasia has increased in recent years, only very few cases of invasive…
Figures from this paper
7 Citations
Negative p53 expression and negative high risk HPV in a 26-year-old lady with vulvar keratinizing squamous cell carcinoma: report of a case
- MedicineEuropean Journal of Gynaecological Oncology
- 2020
A case of 26-year-old lady with keratinizing vulvar squamous cell carcinoma (SCC), in which vulvar intraepithelial neoplasia (VIN) of the simplex type and p53 expression were absent, indicates the necessity to sample any suspicious lesions at this site at any age.
Diseases of the vulva - a clinicopathological
- Medicine
- 2014
The vulval lesions are one of the most neglected especially by the I vulva can harbour lesions starting from a benign bartholin's cyst to aggressive malignancies, more importance should be given to the timely detection, diagnosis and appropriate treatment of these lesions.
Epidemiology, diagnosis and treatment of vulvar intraepithelial neoplasia
- MedicineCurrent opinion in obstetrics & gynecology
- 2002
The incidence of human papilloma virus-related vulvar intraepithelial neoplasia is increasing worldwide and affects older women, who are at risk of invasive cancer, and preliminary results of topical antiviral agents and photodynamic therapy are available.
Lesions of the mons pubis: a review.
- MedicineJournal of lower genital tract disease
- 2015
The mons pubis may become involved in dermatologic conditions or gynecologic lesions affecting the vulva, and a familiarity with these lesions will be helpful if a patient with a lesion of the mons is encountered.
Carcinoma epidermoide de vulva en mujer joven con VPH negativo
- Medicine
- 2016
El cancer de vulva es la cuarta neoplasia mas frecuente del aparato genital, despues del cancer de endometrio, cervix y ovario. Casi siempre se ha vinculado con mujeres entre 70 y 80 anos de edad;…
Pregnancy following radical vulvectomy for carcinoma of the vulva: a case report and literature review.
- MedicineEuropean journal of obstetrics, gynecology, and reproductive biology
- 2011
Vulvar precancers and cancers in the Northern Territory of Australia.
- Political SciencePathology
- 2004
References
SHOWING 1-10 OF 17 REFERENCES
Unsuspected invasive squamous cell carcinoma of the vulva in young women.
- MedicineGynecologic oncology
- 1991
Basaloid and Warty Carcinomas of the Vulva: Distinctive Types of Squamous Cell Carcinoma Frequently Associated with Human Papillomaviruses
- MedicineThe American journal of surgical pathology
- 1993
It is concluded that squamous cell carcinomas of the vulva are etiologically diverse tumors, of which a small but substantial proportion (BC and WC) are related to HPV, whereas the majority (KSC) are not.
Carcinoma in situ of the vulva. A clinicopathologic study of 50 cases.
- MedicineThe Journal of reproductive medicine
- 1986
The authors reviewed 50 cases of carcinoma in situ of the vulva treated at the University of Texas Medical Branch, Galveston, from 1975 to 1984, finding no mortality from invasive cancer.
Invasive squamous carcinoma of the vulva in young patients.
- MedicineGynecologic oncology
- 1982
Prolonged follow-up of patients with invasive squamous carcinoma of the vulva below the age of 35 with "microinvasive" disease has revealed increased susceptibility of the perineum, vagina, and cervix to multiple neoplasms.
Probable Nonpapillomavirus Etiology of Squamous Cell Carcinoma of the Vulva in Older Women: A Clinicopathologic Study Using In Situ Hybridization and Polymerase Chain Reaction
- MedicineInternational journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists
- 1991
The data suggest that vulvar cancer has a diverse etiology which in young women in HPv-related but in older women has little association with HPV, and there appears to be a close correlation between the presence of HPV, specivic subsets of invasive carcinomaand VIN, and age.
Vulvar lichen sclerosus and squamous cell carcinoma: a cohort, case control, and investigational study with historical perspective; implications for chronic inflammation and sclerosis in the development of neoplasia.
- MedicineHuman pathology
- 1998
p53 mutations and clonality in vulvar carcinomas and squamous hyperplasias: evidence suggesting that squamous hyperplasias do not serve as direct precursors of human papillomavirus-negative vulvar carcinomas.
- MedicineHuman pathology
- 1996
Vulvar intraepithelial neoplasia: age, morphological phenotype, papillomavirus DNA, and coexisting invasive carcinoma.
- MedicineHuman pathology
- 1995
Carcinoma of the vulva: epidemiology and pathogenesis.
- MedicineObstetrics and gynecology
- 1992
This review summarizes the epidemiologic, histopathologic, and viral data supporting the division of invasive vulvar carcinomas into distinct subsets and develops strategies to identify women at risk for vulvar cancers that are not associated with HPV.
In situ and invasive vulvar cancer incidence trends (1973 to 1987).
- MedicineAmerican journal of obstetrics and gynecology
- 1992