Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention

@inproceedings{Oka1993VulnerabilityOO,
  title={Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention},
  author={A. Oka and Michel J. Belliveau and Paul A. Rosenberg and Joseph J. Volpe},
  booktitle={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1993}
}
Periventricular white matter injury, the principal variety of brain injury of the human premature infant, involves differentiating oligodendroglia. Nothing is known of the biochemical mechanism of oligodendroglial death in this disorder. Because an early event in periventricular white matter injury is ischemia-induced axonal disruption and because such axonal destruction could lead to a marked increase in local concentrations of glutamate, we evaluated the vulnerability of differentiating… Expand
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