Vulnerability factors among children at risk for anxiety disorders

@article{Merikangas1999VulnerabilityFA,
  title={Vulnerability factors among children at risk for anxiety disorders},
  author={K. Merikangas and S. Avenevoli and L. Dierker and C. Grillon},
  journal={Biological Psychiatry},
  year={1999},
  volume={46},
  pages={1523-1535}
}
  • K. Merikangas, S. Avenevoli, +1 author C. Grillon
  • Published 1999
  • Psychology, Medicine
  • Biological Psychiatry
  • BACKGROUND The high-risk strategy is one of the most powerful approaches for identifying premorbid risk factors and reducing etiologic and phenotypic heterogeneity characteristic of the major psychiatric disorders. METHODS This paper reviews the methods of high-risk research and findings from previous high-risk studies of anxiety. The preliminary results of the 6-8 year follow-up of a high-risk study of 192 offspring of probands with anxiety disorders, substance abuse, and unaffected controls… CONTINUE READING
    213 Citations

    Topics from this paper

    Paper Mentions

    Interventional Clinical Trial
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    ConditionsAnxiety Disorder, Major Depressive Disorder
    InterventionBehavioral
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    References

    SHOWING 1-10 OF 74 REFERENCES
    Offspring at high and low risk for depression and anxiety: mechanisms of psychiatric disorder.
    • 186
    • Highly Influential
    At risk for anxiety: I. Psychopathology in the offspring of anxious parents.
    • D. Beidel, S. Turner
    • Psychology, Medicine
    • Journal of the American Academy of Child and Adolescent Psychiatry
    • 1997
    • 462
    Psychopathology among offspring of parents with substance abuse and/or anxiety disorders: a high-risk study.
    • 243
    Startle modulation in children at risk for anxiety disorders and/or alcoholism.
    • 131
    The risk for early-adulthood anxiety and depressive disorders in adolescents with anxiety and depressive disorders.
    • 1,513
    • PDF
    Influence of parental concordance for psychiatric disorders on psychopathology in offspring.
    • 168
    Psychopathology in Children of Patients with Panic Disorder or Animal Phobia
    • 41
    • Highly Influential
    • PDF
    Co-morbidity and familial aggregation of alcoholism and anxiety disorders.
    • 292
    Genetics of fear and anxiety disorders.
    • I. Marks
    • Psychology, Medicine
    • The British journal of psychiatry : the journal of mental science
    • 1986
    • 65