Voxel-based morphometric analysis of gray matter in first episode schizophrenia.

  title={Voxel-based morphometric analysis of gray matter in first episode schizophrenia.},
  author={Marek Kubicki and Martha Elizabeth Shenton and Dean F. Salisbury and Y Hirayasu and Kiyoto Kasai and Ron Kikinis and Ferenc A. Jolesz and R. W. McCarley},
  volume={17 4},
Voxel-based morphometry (VBM) may afford a more rapid and extensive survey of gray matter abnormalities in schizophrenia than manually drawn region of interest (ROI) analysis, the current gold standard in structural MRI. Unfortunately, VBM has not been validated by comparison with ROI analyses, nor used in first-episode patients with schizophrenia or affective psychosis, who lack structural changes associated with chronicity. An SPM99-based implementation of VBM was used to compare a group of… CONTINUE READING
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