Voxel-based analysis of Alzheimer's disease PET imaging using a triplet of radiotracers: PIB, FDDNP, and FDG

@article{Shin2010VoxelbasedAO,
  title={Voxel-based analysis of Alzheimer's disease PET imaging using a triplet of radiotracers: PIB, FDDNP, and FDG},
  author={Jonghan Shin and Sang-Yoon Lee and Seog Ju Kim and So-Hee Kim and Seong Jin Cho and Young Bo Kim},
  journal={NeuroImage},
  year={2010},
  volume={52 2},
  pages={488-96}
}
Beta amyloid plaques, neurofibrillary tangles, and impaired glucose metabolism are among the most prevalent pathological characteristics of Alzheimer's disease (AD). However, separate visualization of these three AD-related pathologies in living humans has not been conducted. Here, we show that positron emission tomography (PET) imaging using the three radiotracers (11)C-Pittsburgh compound B (PIB), 2-(1-{6-[(2-(18)F-fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene) malononitrile (FDDNP), and 2… CONTINUE READING
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Alzheimer's Disease: A Light at the End of the Tunnel

  • A. J. Robichaud, D. P. Rotella
  • Drug Dev. Res
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