Voxel-Wise Meta-Analysis of Gray Matter Changes in Amyotrophic Lateral Sclerosis

  title={Voxel-Wise Meta-Analysis of Gray Matter Changes in Amyotrophic Lateral Sclerosis},
  author={Dongchao Shen and Li-ying Cui and Jia Bin Fang and Bo Cui and Dawei Li and Hongfei Tai},
  booktitle={Front. Aging Neurosci.},
BACKGROUND Increasing neuroimaging studies have revealed gray matter (GM) anomalies of several brain regions by voxel-based morphometry (VBM) studies in patients with amyotrophic lateral sclerosis (ALS). A voxel-wise meta-analysis was conducted to integrate the reported studies to determine the consistent GM alterations in ALS based on VBM methods. METHODS Ovid Medline, Pubmed, Emabase, and BrainMap database were searched for relevant studies.Data were extracted by two independent researchers… CONTINUE READING
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