Voxel Level Survival Analysis of Grey Matter Volume and Incident Mild Cognitive Impairment or Alzheimer's Disease.

@article{Zeifman2015VoxelLS,
  title={Voxel Level Survival Analysis of Grey Matter Volume and Incident Mild Cognitive Impairment or Alzheimer's Disease.},
  author={Lubov E Zeifman and William F. Eddy and Oscar L. Lopez and Lewis H. Kuller and Cyrus A. Raji and Paul M. Thompson and James T. Becker},
  journal={Journal of Alzheimer's disease : JAD},
  year={2015},
  volume={46 1},
  pages={167-78}
}
The purpose of this study was to identify, at the voxel level, brain regions associated with the time to develop mild cognitive impairment (MCI) or Alzheimer's disease (AD) from normal cognition. We analyzed incident MCI (n = 58) or AD (n = 151) in 292 cognitively normal participants in the Cardiovascular Health Study-Cognition Study (mean age = 79.2 ± 3.6 years). We used segmented, modulated grey matter maps from 3D (spoiled gradient echo) MRI scans obtained in 1998/99 (with clinical follow-up… CONTINUE READING
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