Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis.

@article{Ge2013VorinostatAH,
  title={Vorinostat, a histone deacetylase inhibitor, suppresses dendritic cell function and ameliorates experimental autoimmune encephalomyelitis.},
  author={Zhenzhen Ge and Yurong Da and Zhenyi Xue and Kai Zhang and Hao Zhuang and Meiyu Peng and Yan Li and Wen Li and Alain R Simard and Junwei Hao and Zhi Juan Yao and Rongxin Zhang},
  journal={Experimental neurology},
  year={2013},
  volume={241},
  pages={56-66}
}
Vorinostat, a histone deacetylase inhibitor, has been used clinically as an anticancer drug and also has immunosuppressive properties. However, the underlying mechanisms of effects of vorinostat on central nervous system (CNS) inflammatory diseases remain incomplete. Here, this study investigates the effects of vorinostat on human CD14(+) monocyte-derived… CONTINUE READING