Von Willebrand's disease in the year 2003: towards the complete identification of gene defects for correct diagnosis and treatment.

@article{Castaman2003VonWD,
  title={Von Willebrand's disease in the year 2003: towards the complete identification of gene defects for correct diagnosis and treatment.},
  author={Giancarlo Castaman and Augusto B Federici and Francesco Rodeghiero and Pier M Mannucci},
  journal={Haematologica},
  year={2003},
  volume={88 1},
  pages={94-108}
}
BACKGROUND Von Willebrand's disease (VWD) is an autosomally inherited bleeding disorder caused by a deficiency or abnormality of von Willebrand factor (VWF). VWF is a multimeric adhesive protein which plays an important role in primary hemostasis by promoting platelet adhesion to the subendothelium at sites of vascular injury and platelet-platelet… CONTINUE READING