Voluntary consumption of ethanol in 15 inbred mouse strains

@article{Belknap1993VoluntaryCO,
  title={Voluntary consumption of ethanol in 15 inbred mouse strains},
  author={John K. Belknap and J Christopher F Crabbe and Emmett R. Young},
  journal={Psychopharmacology},
  year={1993},
  volume={112},
  pages={503-510}
}
To determine genetic differences in ethanol consumption, 15 commonly used inbred strains of mice were given ad libitum two-bottle choice between ethanol, 0.2% saccharin, or ethanol plus saccharin in one bottle versus tap water in the other bottle. Three different concentrations of ethanol were used: 3%, 6% and 10% (v/v). Of the 15 strains, the C57BL/6J, C57BR/cdJ and C57L/J strains showed the most consistent higher intake of ethanol either with or without 0.2% saccharin. In marked contrast, the… CONTINUE READING
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