Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts.

@article{Friis2008VolumesensitiveNO,
  title={Volume-sensitive NADPH oxidase activity and taurine efflux in NIH3T3 mouse fibroblasts.},
  author={Martin Barfred Friis and Katrine Gribel Vorum and Ian H Lambert},
  journal={American journal of physiology. Cell physiology},
  year={2008},
  volume={294 6},
  pages={C1552-65}
}
Reactive oxygen species (ROS) are produced in NIH3T3 fibroblasts during hypotonic stress, and H(2)O(2) potentiates the concomitant release of the organic osmolyte taurine (Lambert IH. J Membr Biol 192: 19-32, 2003). The increase in ROS production [5-(and-6)-carboxy-2', 7'-dichlorodihydrofluorescein diacetate fluorescence] is detectable after a reduction in the extracellular osmolarity from 335 mosM (isotonic) to 300 mosM and reaches a maximal value after a reduction to 260 mosM. The swelling… CONTINUE READING
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Reactive oxygen species regulate swelling-induced taurine efflux in NIH3T3 mouse fibroblasts

  • IH Lambert
  • J Membr Biol
  • 2003
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