Volume dependence of airway and tissue impedances in mice.

@article{Sly2003VolumeDO,
  title={Volume dependence of airway and tissue impedances in mice.},
  author={Peter D. Sly and Rachel A. Collins and Cindy Thamrin and Debra J. Turner and Zolt{\'a}n Hantos},
  journal={Journal of applied physiology},
  year={2003},
  volume={94 4},
  pages={1460-6}
}
We measured respiratory input impedance (1-25 Hz) in mice and obtained parameters for airway and tissue mechanics by model fitting. Lung volume was varied by inflating to airway opening pressure (Pao) between 0 and 20 cm H2O. The expected pattern of changes in respiratory mechanics with increasing lung volume was seen: a progressive fall in airway resistance and increases in the coefficients of tissue damping and elastance. A surprising pattern was seen in hysteresivity (eta), with a plateau at… CONTINUE READING

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Initial characterization of lung function in mice deficient in neutrophil proteinases (Abstract)

  • RA Collins, DJ Turner, +4 authors PD. Sly
  • Am J Respir Crit Care Med 165:
  • 2002
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