Volume-Targeted Versus Pressure-Limited Noninvasive Ventilation in Subjects With Acute Hypercapnic Respiratory Failure: A Multicenter Randomized Controlled Trial.

@article{Cao2016VolumeTargetedVP,
  title={Volume-Targeted Versus Pressure-Limited Noninvasive Ventilation in Subjects With Acute Hypercapnic Respiratory Failure: A Multicenter Randomized Controlled Trial.},
  author={Zhixin Cao and Zujin Luo and Anna Hou and Qingrong Nie and Baoyuan Xie and Xiaojie An and Zifen Wan and Xianwei Ye and Yanju Xu and Xisheng Chen and Honghai Zhang and Zhenyang Xu and Jinxiang Wang and Fucheng An and Pengfei Li and Chunxiao Yu and Yandong Liang and Yong-xiang Zhang and Yingmin Ma},
  journal={Respiratory care},
  year={2016},
  volume={61 11},
  pages={1440-1450}
}
BACKGROUND Volume-targeted noninvasive ventilation (VT-NIV), a hybrid mode that delivers a preset target tidal volume (VT) through the automated adjustment of pressure support, could guarantee a relatively constant target VT over pressure-limited noninvasive ventilation (PL-NIV) with fixed-level pressure support. Whether VT-NIV is more effective in improving ventilatory status in subjects with acute hypercapnic respiratory failure (AHRF) remains unclear. Our aim was to verify whether, in… CONTINUE READING