Voltage-sensitive dye recording of action potentials and synaptic potentials from sympathetic microcultures.

@article{Chien1991VoltagesensitiveDR,
  title={Voltage-sensitive dye recording of action potentials and synaptic potentials from sympathetic microcultures.},
  author={C B Chien and Jerome Pine},
  journal={Biophysical journal},
  year={1991},
  volume={60 3},
  pages={697-711}
}
Given the appropriate multicell electrophysiological techniques, small networks of cultured neurons (microcultures) are well suited to long-term studies of synaptic plasticity. To this end, we have developed an apparatus for optical recording from cultured vertebrate neurons using voltage-sensitive fluorescent dyes (Chien, C.-B., and J. Pine. 1991. J. Neurosci. Methods. 38:93-105). We evaluate here the usefulness of this technique for recording action potentials and synaptic potentials in… CONTINUE READING
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