Voltage sensing by fluorescence resonance energy transfer in single cells.

@article{Gonzlez1995VoltageSB,
  title={Voltage sensing by fluorescence resonance energy transfer in single cells.},
  author={J. E. Gonz{\'a}lez and R. Tsien},
  journal={Biophysical journal},
  year={1995},
  volume={69 4},
  pages={
          1272-80
        }
}
A new mechanism has been developed for achieving fast ratiometric voltage-sensitive fluorescence changes in single cells using fluorescence resonance energy transfer. The mechanism is based on hydrophobic fluorescent anions that rapidly redistribute from one face of the plasma membrane to the other according to the Nernst equation. A voltage-sensitive fluorescent readout is created by labeling the extracellular surface of the cell with a second fluorophore, here a fluorescently labeled lectin… Expand
161 Citations
Improved probes for hybrid voltage sensor imaging.
  • 48
  • PDF
Indicators based on fluorescence resonance energy transfer (FRET).
  • R. Tsien
  • Biology, Medicine
  • Cold Spring Harbor protocols
  • 2009
  • 36
Optical measurement of transmembrane potential in intact cardiac tissues using fluorescent resonance energy transfer
pH-Insensitive FRET Voltage Dyes
  • 16
  • PDF
Voltage-dependent Dynamic FRET Signals from the Transverse Tubules in Mammalian Skeletal Muscle Fibers
  • 46
  • Highly Influenced
  • PDF
Monitoring Integrated Activity of Individual Neurons Using FRET-Based Voltage-Sensitive Dyes.
  • 6
  • PDF
...
1
2
3
4
5
...