Voltage-gated sodium channels.

  title={Voltage-gated sodium channels.},
  author={Kevin Kwong and Michael Carr},
  journal={Current opinion in pharmacology},
Voltage-gated sodium channels play a key role in the transmission of sensory information about the status of organs in the periphery. Sensory fibers contain a heterogeneous yet specific distribution of voltage-gated sodium channel isoforms. Major efforts by industry and academic groups are underway to develop medicines that interrupt inappropriate signaling for a number of clinical indications by taking advantage of this specific distribution of channel isoforms. This review highlights recent… CONTINUE READING

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