Voltage-gated potassium currents in myelinating Schwann cells in the mouse.

  title={Voltage-gated potassium currents in myelinating Schwann cells in the mouse.},
  author={Tetsuro Konishi},
  journal={The Journal of physiology},
1. The whole-cell variation of the patch-clamp technique was used to record ionic currents in Schwann cells obtained from enzyme-treated mouse sciatic nerves before and after the onset of myelination. 2. Only outward currents were evoked in embryonic Schwann cells, which had no myelin, at membrane potentials more positive than -40 mV. Neonatal myelinating cells developed depolarization-activated outward currents and hyperpolarization-activated inward currents. For large hyperpolarizations below… CONTINUE READING


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