Voltage gated ionic channels in rat cultured astrocytes, reactive astrocytes and an astrocyte-oligodendrocyte progenitor cell.

@article{Bevan1987VoltageGI,
  title={Voltage gated ionic channels in rat cultured astrocytes, reactive astrocytes and an astrocyte-oligodendrocyte progenitor cell.},
  author={Stuart Bevan and R. Matthews Lindsay and Martin Nicholas Perkins and Martin C. Raff},
  journal={Journal de physiologie},
  year={1987},
  volume={82 4},
  pages={
          327-35
        }
}
Astrocytes (both type 1 and type 2), cultured from the central nervous system of newborn or 7 day old rats show voltage gated sodium and potassium channels that are activated when the membrane is depolarized to greater than -40 mV. The sodium channels in these cells have an h-infinity curve similar to that of nodal membranes but the activation (peak current-voltage) curves are shifted along the voltage axis by about +30 mV. These sodium currents are blocked only by high concentrations of… CONTINUE READING

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