Voltage-gated Ca2+ currents in rat gastric enterochromaffin-like cells.

  title={Voltage-gated Ca2+ currents in rat gastric enterochromaffin-like cells.},
  author={Johannes Bufler and Geyong Cheol Choi and Christian Franke and W. Schepp and Christian Prinz},
  journal={The American journal of physiology},
  volume={274 2 Pt 1},
Enterochromaffin-like (ECL) cells are histamine-containing endocrine cells in the gastric mucosa that maintain a negative membrane potential of about -50 mV, largely due to voltage-gated K+ currents [D. F. Loo, G. Sachs, and C. Prinz. Am. J. Physiol. 270 (Gastrointest Liver Physiol. 33): G739-G745, 1996]. The current study investigated the presence of voltage-gated Ca2+ channels in single ECL cells. ECL cells were isolated from rat fundic mucosa by elutriation, density gradient centrifugation… CONTINUE READING


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