Voltage-driven DNA translocations through a nanopore.

  title={Voltage-driven DNA translocations through a nanopore.},
  author={Amit Meller and Lucas Gregorio Niv{\'o}n and Daniel Branton},
  journal={Physical review letters},
  volume={86 15},
We measure current blockade and time distributions for single-stranded DNA polymers during voltage-driven translocations through a single alpha-hemolysin pore. We use these data to determine the velocity of the polymers in the pore. Our measurements imply that, while polymers longer than the pore are translocated at a constant speed, the velocity of shorter polymers increases with decreasing length. This velocity is nonlinear with the applied field. Based on this data, we estimate the effective… CONTINUE READING