Voltage-dependent potassium channels in activated rat microglia.

  title={Voltage-dependent potassium channels in activated rat microglia.},
  author={Wolfgang N{\"o}renberg and Peter J. Gebicke-Haerter and P{\'e}ter Ill{\'e}s},
  journal={The Journal of physiology},
  volume={475 1},
1. Voltage-dependent currents of untreated (proliferating) and lipopolysaccharide (LPS)-treated rat microglial cells in culture were recorded using the whole-cell patch-clamp technique. 2. Membrane potentials showed prominent peaks at -35 mV and -70 mV. Membrane potentials of LPS-treated cells alternated between the two values. This may be due to a negative slope region of the I-V relation resulting in two zero current potentials. 3. From a holding potential of -70 mV, hyperpolarizing steps… CONTINUE READING


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