Voltage-dependent gating of single sodium channels from mammalian neuroblastoma cells.

@article{Aldrich1987VoltagedependentGO,
  title={Voltage-dependent gating of single sodium channels from mammalian neuroblastoma cells.},
  author={Richard W. Aldrich and Charles F. Stevens},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1987},
  volume={7 2},
  pages={
          418-31
        }
}
Single sodium channel currents have been studied in cell-attached patches from the mouse neuroblastoma cell line N1E115. Distributions of open duration, latency until first opening, and the average probability of a channel being open after a voltage step, p(t), were analyzed and compared to predicted distributions from various kinetic models for voltage-dependent gating. It was found that, over most of the voltage range under which channel gating occurs, the slow steps in gating are opening… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 53 CITATIONS

Properties of appropriately and inappropriately expressed sodium channels in squid giant axon and its somata.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1989
VIEW 1 EXCERPT
CITES BACKGROUND
HIGHLY INFLUENCED

Spatial mismatch between the Na+ flux and spike initiation in axon initial segment.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2013
VIEW 1 EXCERPT
CITES BACKGROUND

FILTER CITATIONS BY YEAR

1988
2018

CITATION STATISTICS

  • 1 Highly Influenced Citations

  • 100% Increase in citations per year in 2018 over 2017

References

Publications referenced by this paper.
SHOWING 1-10 OF 38 REFERENCES

Inactivation viewed through single sodium channels

  • The Journal of general physiology
  • 1984
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Sodium and calcium channels in bovine chromaffin cells.

  • The Journal of physiology
  • 1982
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Interaction between sodium channels in mouse neuroblastoma cells

  • European Biophysics Journal
  • 1985
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Statistical properties of single sodium channels

  • The Journal of general physiology
  • 1984
VIEW 2 EXCERPTS
HIGHLY INFLUENTIAL

Voltage clamp analysis of sodium channels in normal and scorpion toxin-resistant neuroblastoma cells.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1984
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Inactivation of open and closed sodium channels determined separately.

  • Cold Spring Harbor symposia on quantitative biology
  • 1983
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Modification of single Na+ channels by batrachotoxin.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1982
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…