Voltage-dependent gating of gap junction channels in embryonic chick ventricular cell pairs.

@article{Veenstra1990VoltagedependentGO,
  title={Voltage-dependent gating of gap junction channels in embryonic chick ventricular cell pairs.},
  author={Richard D. Veenstra},
  journal={The American journal of physiology},
  year={1990},
  volume={258 4 Pt 1},
  pages={C662-72}
}
The dependence of macroscopic gap junctional conductance (Gj) on transjunctional voltage (Vj) was studied in paired myocytes after enzymatic dissociation of 7-day-old embryonic chick ventricles. The membrane voltage of both cells was independently controlled by separate patch-clamp circuits in the whole cell configuration. Two distinctive unitary junctional conductances were identified in recordings from seven different cell pairs. The larger channel had a mean conductance of 166 +/- 37 pS (n… CONTINUE READING

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