Voltage-dependent calcium channels in the rat retina: involvement in NMDA-stimulated influx of calcium.

@article{Melena2001VoltagedependentCC,
  title={Voltage-dependent calcium channels in the rat retina: involvement in NMDA-stimulated influx of calcium.},
  author={Jos{\'e} Melena and Neville N Osborne},
  journal={Experimental eye research},
  year={2001},
  volume={72 4},
  pages={393-401}
}
Rises in intracellular Ca2+ induced by activation of glutamate receptors are of ultimate importance for neuronal excitability and pathophysiological processes. In the present study, we aimed to elucidate the types of voltage-dependent Ca2+ channels involved in the NMDA-stimulated influx of Ca2+ into the isolated rat retina by using selective blockers. Additionally, the number of binding sites for radioligands labelling L- ([3H]nitrendipine), N- ([125I]omega-conotoxin MVIIA) and P/Q-type ([125I… CONTINUE READING

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