Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes.

Abstract

The spontaneous activity of pacemaker cells in the sino-atrial node controls the heart rhythm and rate under physiological conditions. Compared to working myocardial cells, pacemaker cells express a specific array of ionic channels. The functional importance of different ionic channels in the generation and regulation of cardiac automaticity is currently… (More)

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Cite this paper

@article{Mangoni2006VoltagedependentCC, title={Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes.}, author={Matteo Elia Mangoni and Brigitte Couette and Laurine Marger and Emmanuel Bourinet and Joerg Striessnig and Jo{\"e}l Nargeot}, journal={Progress in biophysics and molecular biology}, year={2006}, volume={90 1-3}, pages={38-63} }