Voltage-dependent anion-selective channel (VDAC) in the plasma membrane.

@article{Pinto2010VoltagedependentAC,
  title={Voltage-dependent anion-selective channel (VDAC) in the plasma membrane.},
  author={Vito de Pinto and Angela Anna Messina and Darius J. R. Lane and Alfons Lawen},
  journal={FEBS letters},
  year={2010},
  volume={584 9},
  pages={1793-9}
}
Voltage-dependent anion channels (VDACs) have originally been characterized as mitochondrial porins. Starting in the late 1980s, however, evidence began to accumulate that VDACs can also be expressed in plasma membranes. In this review, we briefly revisit the historical milestones in the discovery of plasma membrane-bound VDAC, and we critically analyze the evidence for VDAC plasma membrane localization obtained from various purification strategies and recently from plasma membrane proteomics… CONTINUE READING

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