Voltage-dependence of drug-induced conductance in frog neuromuscular junction.

  title={Voltage-dependence of drug-induced conductance in frog neuromuscular junction.},
  author={Erwin Neher and Bert J. Sakmann},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={72 6},
Membrane currents from voltage-clamped frog muscle fibers were recorded during iontophoretic application of steady doses of carbachol, acetylcholine, and suberyldicholine to the endplate region. In the presence of these drugs, an exponentially relaxing current was observed after step changes of membrane potential. The time constant of relaxation was found to be voltage-dependent. It was equal to the time constant obtained from the autocorrelation function of drug-induced conductance… CONTINUE READING
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" The effect of voltage on the time course of endplate currents

  • P. Adams
  • 1972

The effect of internal and external potassium concentration on the membrane potential of frog muscle

  • A. Takeuchi, N. Takeuchi
  • 1956

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