Voltage dependence of G-protein-mediated inhibition of high-voltage-activated calcium channels in rat pituitary melanotropes.

@article{Keja1994VoltageDO,
  title={Voltage dependence of G-protein-mediated inhibition of high-voltage-activated calcium channels in rat pituitary melanotropes.},
  author={J A Keja and Karel S. Kits},
  journal={Neuroscience},
  year={1994},
  volume={62 1},
  pages={281-9}
}
Dopamine D2 receptor stimulation inhibited high-threshold, slowly inactivating (L-type) barium currents of isolated, rat pituitary melanotropes in primary culture. The extent of inhibition depended on the concentration of LY 171555 applied. Current activation in the presence of LY 171555 was described by two time constants, a fast one, also observed under control conditions, and a slow one, induced by LY 171555. The slow time constant did not depend on the concentration of LY 171555. Guanosine… CONTINUE READING