Voltage activation and hysteresis of the non-selective voltage-dependent channel in the intact human red cell.

@article{Bennekou2004VoltageAA,
  title={Voltage activation and hysteresis of the non-selective voltage-dependent channel in the intact human red cell.},
  author={Poul Bennekou and Trine L Barksmann and Lars R.D. Jensen and Berit I. Kristensen and Palle Christophersen},
  journal={Bioelectrochemistry},
  year={2004},
  volume={62 2},
  pages={181-5}
}
Suspension of intact human red cells in media with low chloride and sodium concentrations (isotonic sucrose substitution) results in strongly inside positive membrane potentials, which activate the voltage-dependent non-selective cation (NSVDC) channel. By systematic variation of the initial Nernst potentials for chloride (degree of ion substitution) as well as the chloride conductance (block by NS1652), and by exploiting the interplay between the Ca(2+)-permeable NSVDC channel, the Ca(2… CONTINUE READING

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