Voltage-activated sodium currents in acutely isolated mouse vestibular ganglion neurones.

  title={Voltage-activated sodium currents in acutely isolated mouse vestibular ganglion neurones.},
  author={Christian Chabbert and J M Chambard and Jean Valmier and Alain Sans and Gilles Desmadryl},
  volume={8 5},
Voltage-activated sodium currents (INa) in vestibular ganglion neurones acutely isolated from postnatal mice were investigated using the whole-cell configuration of the patch-clamp technique. Under recording conditions designed to allow the complete isolation of INa depolarizations from a holding potential of -80 mV revealed a fast inactivating inward current which was activated around -60 mV and exhibited maximum peak current around -30 mV. This current was eliminated when the cells were… CONTINUE READING

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