Voltage‐gated calcium channels play crucial roles in the glutamate‐induced phase shifts of the rat suprachiasmatic circadian clock

@article{Kim2005VoltagegatedCC,
  title={Voltage‐gated calcium channels play crucial roles in the glutamate‐induced phase shifts of the rat suprachiasmatic circadian clock},
  author={Do Young Kim and Hee Joo Choi and Jeong Sook Kim and Yoon-Sik Kim and Do Ung Jeong and Hyung-Cheul Shin and Mi Jin Kim and Hee Chul Han and Seung Kil Hong and Yang In Kim},
  journal={European Journal of Neuroscience},
  year={2005},
  volume={21}
}
The resetting of the circadian clock based on photic cues delivered by the glutamatergic retinohypothalamic tract is an important process helping mammals to function adaptively to the daily light–dark cycle. To see if the photic resetting relies on voltage‐gated Ca2+ channels (VGCCs), we examined the effects of VGCC blockers on the glutamate‐induced phase shifts of circadian firing activity rhythms of suprachiasmatic nucleus (SCN) neurons in hypothalamic slices. First, we found that a cocktail… 
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