Volatile fingerprints of cancer specific genetic mutations.

  title={Volatile fingerprints of cancer specific genetic mutations.},
  author={Nir Peled and Orna Barash and Ulrike Tisch and Radu Ionescu and Yoav Y. Broza and Maya Ilouze and Jane Mattei and Paul A. Bunn and Fred R Hirsch and Hossam Haick},
  journal={Nanomedicine : nanotechnology, biology, and medicine},
  volume={9 6},
UNLABELLED We report on a new concept for profiling genetic mutations of (lung) cancer cells, based on the detection of patterns of volatile organic compounds (VOCs) emitted from cell membranes, using an array of nanomaterial-based sensors. In this in-vitro pilot study we have derived a volatile fingerprint assay for representative genetic mutations in cancer cells that are known to be associated with targeted cancer therapy. Five VOCs were associated with the studied oncogenes, using… CONTINUE READING