Vogt–Koyanagi–Harada disease: inquiry into the genesis of a disease name in the historical context of Switzerland and Japan

@article{Herbort2007VogtKoyanagiHaradaDI,
  title={Vogt–Koyanagi–Harada disease: inquiry into the genesis of a disease name in the historical context of Switzerland and Japan},
  author={Carl P. Herbort and Manabu Mochizuki},
  journal={International Ophthalmology},
  year={2007},
  volume={27},
  pages={67-79}
}
PurposeTo delineate the historical steps associated with the genesis of the name and the definition of Vogt–Koyanagi–Harada (VKH) disease.MethodsA bibliographical review of the major publications that were relevant to the original development of the name of the clinical entity known today as Vogt–Koyanagi–Harada disease, in the historical context of the early 20th century.ResultsThree distinct time periods can be considered to be important in terms of providing a historical perspective on VKH… 
Vogt-Koyanagi-Harada syndrome.
Vogt-Koyanagi-Harada Syndrome
TLDR
The prognosis for VKH syndrome was greatly improved, future prospective, controlled, multi-center studies are needed to determine the optimal treatment regime for this disease, and the IL17/23 pathway may provide a novel therapeutic target to control inflammation inVKH syndrome.
Vogt-Koyanagi-Harada syndrome: what neurologists need to know
TLDR
Vogt-Koyanagi-Harada syndrome is a multisystem disorder that typically presents with bilateral uveitis, often associated with neurological and/or audiological features, and there does appear to be a genetic influence, with increased susceptibility in people with certain HLA haplotypes, particularly HLA DRB1*0405 and HLA-DQ4.
Precise, simplified diagnostic criteria and optimised management of initial-onset Vogt–Koyanagi–Harada disease: an updated review
TLDR
A novel perspective of VKH disease was provided, taking into account recent developments in the understanding of the disease and crucial progress in investigational modalities of the choroid, which has led to new, simpler diagnostic criteria.
Vogt-Koyanagi-Harada syndrome: a rheumatologic perspective
TLDR
The success in preserving the vision of VKH syndrome patients hinges on early diagnosis and aggressive treatment that includes immunomodulatory therapy, and as a result ophthalmologists are increasingly referring such patients to specialists.
Vogt-Koyanagi-Harada disease: review of a rare autoimmune disease targeting antigens of melanocytes
TLDR
The current review discusses the general features of VKHD, including epidemiology, classification into categories, differential diagnosis and current therapeutic approaches.
Vogt-Koyanagi-Harada disease
A Case Report on Vogt-Koyanagi-Harada Disease Seen at a Tertiary Hospital in the Philippines
TLDR
The main objective of presenting this classic case of Vogt-Koyanagi-Harada disease is describing its chronic systemic course, and the possible medical and surgical management for the disease and its complications.
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References

SHOWING 1-10 OF 37 REFERENCES
Vogt-Koyanagi-Harada Syndrome
HLA class II genes in Vogt-Koyanagi-Harada disease.
TLDR
It can be postulated that VKH is a disease of combined allelic predisposition in which DQA1*0301 acts as the primary and HLA-DR4 acts as an additive factor in the development of the disease.
Indocyanine green angiography in Vogt–Koyanagi–Harada disease: angiographic signs and utility in patient follow-up
TLDR
Choroidal inflammation shown by ICG angiography can be suppressed completely by initial high-dose inflammation suppressive therapy, however, recurrent subclinical choroidalinflammatory activity is detected at the end of the tapering period in a high proportion of cases.
Tyrosinase Family Proteins Are Antigens Specific to Vogt-Koyanagi-Harada Disease1
TLDR
It is found that exposure of lymphocytes from patients with VKH disease to peptides (30-mer) derived from the tyrosinase family proteins led to significant proliferation of the lymphocytes.
Identification of autoreactive T cells in Vogt-Koyanagi-Harada disease.
TLDR
The autoreactive T cells against tyrosinase and/or TRP1 may contribute to the development of VKH disease.
HLA-DRB1 typing of Vogt-Koyanagi-Harada's disease by PCR-RFLP and the strong association with DRB1*0405 and DRB1*0410.
TLDR
To clarify molecular genetic mechanism underlying the susceptibility/resistance to VKH disease, HLA-DNA typing of DR antigens (DRB1 genotyping) by the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method was performed and it was found that DRB1*0405 showed a significant association withVKH disease.
[75th annual session of the Swiss Ophthalmological Society; on its founding and its founders].
  • F. Rintelen
  • Medicine
    Klinische Monatsblatter fur Augenheilkunde
  • 1983
TLDR
The author concludes this paper by pointing out the importance of the "unknown ophthalmologist, whose quiet, unselfish day-to-day work in practice represents a contribution to culture in the sense of creative human activity".
Immunologic analysis of cerebrospinal fluid lymphocytes in Vogt-Koyanagi-Harada disease.
TLDR
The immunologic aspects of Vogt-Koyanagi-Harada disease are focused upon by comparing the cytotoxic activity of peripheral blood leukocytes to that of cerebrospinal fluidLeukocytes (CSFL) against the human melanoma cell line (P-36) and the human cervical carcinomacell line (HeLa-S3).
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