Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance.

@article{Kawamori2009VogliboseFP,
  title={Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance.},
  author={Ryuzo Kawamori and Naoko Tajima and Yasuhiko Iwamoto and Atsunori Kashiwagi and Kazuaki Shimamoto and Kohei Kaku},
  journal={Lancet},
  year={2009},
  volume={373 9675},
  pages={1607-14}
}
BACKGROUND The increased prevalence of type 2 diabetes mellitus is a major concern for health providers. We therefore assessed whether voglibose, an alpha-glucosidase inhibitor, could prevent the development of type 2 diabetes in high-risk Japanese individuals with impaired glucose tolerance. METHODS 1780 eligible patients on a standard diet and taking regular exercise with impaired glucose tolerance were randomly assigned to oral voglibose 0.2 mg three times a day (n=897) or placebo (n=883… CONTINUE READING
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