Vitronectin inhibits the thrombotic response to arterial injury in mice.

@article{Fay1999VitronectinIT,
  title={Vitronectin inhibits the thrombotic response to arterial injury in mice.},
  author={William P. Fay and Andrew C. Parker and M Najeeb-Ur-Rab Ansari and Xunzhen Zheng and David Ginsburg},
  journal={Blood},
  year={1999},
  volume={93 6},
  pages={
          1825-30
        }
}
Vitronectin (VN) binds to plasminogen activator inhibitor-1 (PAI-1) and integrins and may play an important role in the vascular response to injury by regulating fibrinolysis and cell migration. However, the role of VN in the earliest response to vascular injury, thrombosis, is not well characterized. The purpose of this study was to test the hypothesis that variation in vitronectin expression alters the thrombotic response to arterial injury in mice. Ferric chloride (FeCl3) injury was used to… CONTINUE READING

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A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998