Vitronectin: a matrix support factor for human limbal epithelial progenitor cells.

@article{Echevarria2011VitronectinAM,
  title={Vitronectin: a matrix support factor for human limbal epithelial progenitor cells.},
  author={Timothy Jerome Echevarria and Sharron Chow and Stephanie Watson and Denis Wakefield and Nick Di Girolamo},
  journal={Investigative ophthalmology & visual science},
  year={2011},
  volume={52 11},
  pages={
          8138-47
        }
}
PURPOSE The authors recently developed a therapeutic technique for patients with limbal stem cell deficiency by harvesting ocular surface stem cells (SCs), expanding them on therapeutic contact lenses (CLs), and applying them to diseased corneas. The present study determined the proteins that bind to CLs and whether such factors, along with transplanted cells, are critical determinants for corneal rehabilitation using this method. METHODS Therapeutic CLs were exposed to human serum, and… CONTINUE READING

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