Vitreous fluorophotometry in patients with senile macular degeneration.

  title={Vitreous fluorophotometry in patients with senile macular degeneration.},
  author={Saul Merin and Norman Paul Blair and Mark O. M. Tso},
  journal={Investigative ophthalmology & visual science},
  volume={28 4},
Twenty-two phakic eyes of 16 patients with varying stages of senile macular degeneration (SMD) underwent vitreous fluorophotometry. The upper tolerance limit of the penetration ratio in 17 eyes of 17 age-matched controls was 6.33 X 10(-6) min-1. Ten of the 22 eyes with SMD had values exceeding this, indicating abnormal blood-retinal barrier function. When the fluorescence recorded in the vitreous but not related to the local intravitreal dye was evaluated, it was greater in those eyes with more… CONTINUE READING