Vitiligo in a Patient Treated with Interferon Alpha-2a for Behçet's Disease

  title={Vitiligo in a Patient Treated with Interferon Alpha-2a for Behçet's Disease},
  author={Esra Guney and Gulunay Akcali and Betul Ilkay Sezgin Akcay and Cihan Unlu and Gurkan Erdogan and Tahir Kansu Bozkurt and H{\"u}seyin Bayramlar},
  booktitle={Case reports in medicine},
Behçet's disease (BD) and vitiligo are diseases of unknown etiology. Interferon (IFN) alpha therapy is commonly used in Behçet uveitis. Interferon treatment in various diseases have also been observed causing certain autoimmune diseases such as vitiligo because of its immunomodulatory activity. The association between IFN therapy and vitiligo has been reported in the literature. We report a 21-year-old man with BD in whom vitiligo occurred during IFN treatment. To the best of our knowledge… CONTINUE READING

Figures and Topics from this paper.


Publications referenced by this paper.


S. Onal, H. Kazokoglu
  • Koc et al., “Long-term efficacy and safety of low-dose and dose-escalating interferon alfa-2a therapy in refractory Behçet uveitis,” Archives of Ophthalmology, vol. 129, no. 3, pp. 288–294
  • 2011

Long - term e ffi cacy and safety of low - dose and dose - escalating interferon alfa - 2 a therapy in refractory Behçet uveitis

M. Zierhut I. Kötter, A. K. Eckstein
  • Archives of Ophthalmology
  • 2011


G. Sobac, U. Erdem
  • H. Durukan et al., “Safety and effectiveness of interferon alpha-2a in treatment of patients with Case Reports in Medicine 3 behet’s uveitis refractory to conventional treatments,” Ophthalmology, vol. 117, no. 7, pp. 1430–1435
  • 2010

and A

V. Arya, M. Bansal, L. Girard, S. Arya
  • Valluri, “Vitiligo at injection site of PEG-IFN-α 2a in two patients with chronic hepatitis C: case report and literature review,” Case Reports in Dermatology, vol. 2, no. 2, pp. 156–164
  • 2010

and A

I. Hamadah, Y. Binamer, F. M. Sanai, A. A. Abdo
  • Alajlan, “Interferon-induced vitiligo in hepatitis C patients: a case series,” International Journal of Dermatology, vol. 49, no. 7, pp. 829–833
  • 2010


D. Mendes, M. Correia
  • Barbedo et al., “Behçet’s disease— a contemporary review,” Journal of Autoimmunity, vol. 32, no. 3-4, pp. 178–188
  • 2009