Vitiligo: symptoms, pathogenesis and treatment.

  title={Vitiligo: symptoms, pathogenesis and treatment.},
  author={Abdolhossein Ghafourian and Sobhan Ghafourian and Nourkhoda Sadeghifard and Reza Mohebi and Y Shokoohini and Sadaf Nezamoleslami and Rukman Awang Hamat},
  journal={International journal of immunopathology and pharmacology},
  volume={27 4},
Vitiligo is an acquired cutaneous disorder of pigmentation, with an incidence of 0.5% to 2% worldwide. There are three major hypotheses for the pathogenesis of vitiligo that are not exclusive of each other: biochemical/cytotoxic, neural and autoimmune. Recent data provide strong evidence supporting an autoimmune pathogenesis of vitiligo. As vitiligo can have a major effect on quality of life, treatment can be considered and should preferably begin early when then disease is active. Current… CONTINUE READING