Vitamins C and E improve endothelial dysfunction in intrauterine-undernourished rats by decreasing vascular superoxide anion concentration.

@article{Franco2003VitaminsCA,
  title={Vitamins C and E improve endothelial dysfunction in intrauterine-undernourished rats by decreasing vascular superoxide anion concentration.},
  author={Maria do Carmo Franco and Eliana Akamine and Maria Aparecida de Oliveira and Zuleica Bruno Fortes and Rita de C{\'a}ssia Aleixo Tostes and Maria Helena Catelli de Carvalho and Dorothy Nigro},
  journal={Journal of cardiovascular pharmacology},
  year={2003},
  volume={42 2},
  pages={211-7}
}
Epidemiological studies suggest that intrauterine undernutrition plays an important role in the development of arterial hypertension in adulthood. Ascorbic acid (vitamin C) and alpha-tocopherol (vitamin E) have antioxidant properties that could improve redox-sensitive vascular changes associated with hypertension. The authors determined whether vitamins C and E treatments ameliorate the hypertension and vascular function in male rats submitted to intrauterine undernutrition. Pregnant Wistar… CONTINUE READING

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