Vitamins, Homocysteine and Cardiovascular Risk

@article{Graham2002VitaminsHA,
  title={Vitamins, Homocysteine and Cardiovascular Risk},
  author={Ian M. Graham and Patrick O'Callaghan},
  journal={Cardiovascular Drugs and Therapy},
  year={2002},
  volume={16},
  pages={383-389}
}
A raised plasma level of the amino acid homocysteine is associated with increased risk of cardiovascular disease. This association may be causal—it is biologically plausible, fairly strong, graded, and an increase in plasma homocysteine preceeds the onset of vascular disease. Plasma homocysteine levels are controlled by genetic and nutritional factors, notably folate, vitamin B12 and vitamin B6 intakes. Folic acid in particular lowers plasma homocysteine levels by about 25%. It is not known if… CONTINUE READING
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