Vitamin supplementation in the secondary prevention of venous thromboembolism: about the VITRO study.

We read with great interest and expectation the article by den Heijer et al1 on a randomized, placebo-controlled double-blind trial in the secondary prevention of venous thromboembolism. We point out some issues to be clarified by the authors, and a general comment. (1) The authors do not give any information on the prevalence of thrombophilic polymorphisms… (More)