Vitamin and mineral supplementation in Down's syndrome.

  title={Vitamin and mineral supplementation in Down's syndrome.},
  author={Forrest C. Bennett and S. McClelland and Elinor Kriegsmann and Lydia Andrus and Clifford J. Sells},
  volume={72 5},
The claim that large, nonspecific doses of vitamins and minerals improve the performance of mentally retarded children has recently reappeared in both the scientific literature and the public media. This hypothesis was examined in a double-blind, case-control study involving 20 home-reared children with Down's syndrome between 5 and 13 years of age. Children were randomly assigned by matched pairs to either a vitamin/mineral group or placebo group for an 8-month study period. No significant… 
Vitamin Therapy and Children with down Syndrome: A Review of Research
The claim that large doses of vitamin-mineral supplements benefit mentally retarded children has captured the attention of the general public and the medical profession. A study by Harrell, Capp,
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The efforts of the authors to replicate the Harrell et al. research are documents and, although no significant differences were found between active treatment groups and control groups at study's end, a thorough comparison is made between the two research efforts.
Complementary and alternative therapies for Down syndrome.
  • N. Roizen
  • Medicine, Psychology
    Mental retardation and developmental disabilities research reviews
  • 2005
There is a lack of well-designed scientific studies on the use of alternative therapies in individuals with Down syndrome, but antioxidants hold theoretical promise for treatment of the cognitive, immune, malignancy, and premature aging problems associated with Down Syndrome.
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The quality of the research on vitamins, minerals, hormones, and dietary treatments for individuals with MRDD is found to be overwhelmingly anecdotal and poorly controlled, and the outcomes not strongly supportive of their efficacy.
Nutritional supplementation in Down syndrome: theoretical considerations and current status.
Down syndrome (DS) is the most common inherited cause of learning disability, and affected individuals are more prone to infections, leukaemia, congenital heart disease and other anomalies, thyroid
Vitamin, Mineral, and Dietary Treatments
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