Vitamin K uptake in hepatocytes and hepatoma cells.


Hepatocellular carcinoma (HCC) or hepatoma cells have impaired ability to perform vitamin K-dependent carboxylation reactions. Vitamin K can also inhibit growth of HCC cells in vitro. Both carboxylation and growth inhibition are vitamin K dose dependent. We used rat hepatocytes, a vitamin K-growth sensitive (MH7777) and a vitamin K-growth resistant (H4IIE… (More)


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@article{Li2002VitaminKU, title={Vitamin K uptake in hepatocytes and hepatoma cells.}, author={Zhong-Qian Li and Feng-yun He and Christine J Stehle and Ziqiu Wang and Siddhartha P Kar and Frances M Finn and Brian I Carr}, journal={Life sciences}, year={2002}, volume={70 18}, pages={2085-100} }