Vitamin K status and cardiovascular events or mortality: A meta-analysis

  title={Vitamin K status and cardiovascular events or mortality: A meta-analysis},
  author={S. Zhang and Leilei Guo and Chunxiao Bu},
  journal={European Journal of Preventive Cardiology},
  pages={549 - 553}
  • S. Zhang, Leilei Guo, Chunxiao Bu
  • Published 2019
  • Medicine
  • European Journal of Preventive Cardiology
  • Vitamin K serving as a cofactor modulates calcification by activating calcification inhibitors such as matrix Gla protein (MGP); vascular vitamin K deficiency could therefore increase calcium deposition, leading to the occurrence of major adverse cardiovascular events. The current paper is mainly focused on two isoforms of MGP: desphospho-uncarboxylated MGP (dp-ucMGP) and desphospho-carboxylated MGP (dpcMGP). High levels of plasma dp-ucMGP are perceived as a proxy for vitamin K deficiency. As… CONTINUE READING

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    Publications referenced by this paper.
    European Guidelines on Cardiovascular Disease Prevention
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