Vitamin K, circulating cytokines, and bone mineral density in older men and women.

@article{Shea2008VitaminKC,
  title={Vitamin K, circulating cytokines, and bone mineral density in older men and women.},
  author={Mary Kyla Shea and Gerard E. Dallal and Bess Dawson-Hughes and Jos{\'e} M. Ordov{\'a}s and Christopher J. O'Donnell and Caren M. Gundberg and James W. Peterson and Sarah L. Booth},
  journal={The American journal of clinical nutrition},
  year={2008},
  volume={88 2},
  pages={356-63}
}
BACKGROUND Vitamin K modulates cytokines involved in bone turnover, including interleukin-6 (IL-6) and osteoprotegerin in vitro. OBJECTIVE The objective of this study was to assess 1) associations between measures of vitamin K status [plasma phylloquinone and serum percentage of undercarboxylated osteocalcin (%ucOC)] and IL-6, osteoprotegerin, and C-reactive protein (CRP) concentrations and 2) the effect of daily 500 mug phylloquinone supplementation for 3 y on cytokine concentrations… CONTINUE READING

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