Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells

@article{Patacsil2011VitaminES,
  title={Vitamin E succinate inhibits survivin and induces apoptosis in pancreatic cancer cells},
  author={Dorrelyn Patacsil and Sylvester N. Osayi and Anh Thu Tran and Francisco R. Saenz and Lydia Yimer and Ayesha N. Shajahan and Prafulla C. Gokhale and Mukesh Verma and Robert Clarke and Subhash Chand Chauhan and Deepak Kumar Vijaya Kumar},
  journal={Genes & Nutrition},
  year={2011},
  volume={7},
  pages={83-89}
}
Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States. Identifying novel chemotherapeutic and chemopreventive approaches is critical in the prevention and treatment of cancers such as pancreatic cancer. Vitamin E succinate (VES) is a redox-silent analog of the fat-soluble vitamin alpha-tocopherol. In the present study, we explored the antiproliferative action of VES and its effects on inhibitor of apoptosis proteins in pancreatic cancer cells. We show that… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-8 of 8 extracted citations

Casticin induces human glioma cell death through apoptosis and mitotic arrest.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology • 2013

References

Publications referenced by this paper.
Showing 1-10 of 22 references

Survivin and IAP proteins in cell-death mechanisms.

The Biochemical journal • 2010
View 2 Excerpts
Highly Influenced

Cancer statistics , 2010

R Siegel, J Xu, E Ward
CA Cancer J Clin • 2010

Similar Papers

Loading similar papers…